Infrastructure
“Commitment to Precision and Quality, Delivering Medicine that Heals and Empowers”
Cosmas has developed a sophisticated manufacturing facility in Ludhiana equipped with ultra modern infrastructure and world class technology. Also, it has manufacturing facility at Baddi , catering to General block which has Tablets, Capsules , Oral Liquids and Dry Syrup in it.
The oncology , beta lactum and Cepha blocks are completely separated i.e. All blocks are structurally isolated and use completely seperate air handling system.
Cephalosporin/Betalactam
- Plant specially designed at low RH & temperature, most suitable for Clavulanic Acid preparation.
- Temperature, Humidity & Pressure differential - monitored online on BMS system.
- High production capacity.
- Automatic powder transfer system in OSD in a closed loop.
- Injectable lines with latest closed RABS technology.
- Water system completely fitted with “Zero Dead Lag Valves” of GEMU (Germany) to avoid microbial growth.
- AHU’s fitted with BIBO system.
- Imported dehumidification system.
Block Capacity
| S.NO | DOSAGE FORM | CAPACITY (Per Shift) |
|---|---|---|
|
1 |
Tablets |
10,00,000 |
|
2 |
Capsules |
500,000 |
|
3 |
Dry Powder Injection |
200,000 |
|
4 |
Dry Syrup |
40,000 Bottles with 30ml Capacity |
Oncology
- Compatible with OEL Level - 5
- All the machines have been imported from IMA Italy
- Powder transfer system, specially designed for compatible with exposure levels, having WIP and CIP system
- Facility of lyophilisation with IMA Edwards Lyo
- All the machines are 21-CFR, Part – 11 compliant
Oncology
- Compatible with OEL Level - 5
- All the machines have been imported from IMA Italy
- Powder transfer system, specially designed for compatible with exposure levels, having WIP and SIP system
- Facility of lyophilisation with IMA Edwards Lyo
- All the machines are 21-CFR, Part – 11 compliant
Block Capacity
| S.NO | DOSAGE FORM | CAPACITY (Per Shift) |
|---|---|---|
|
1 |
Lyophilized Injection -10 ml |
30,000 vials per cycle |
|
2 |
Liquid Injection |
48000 |
We have ultra modern manufacturing facility at Baddi, catering to General Block which has Tablets, Capsules, Oral Liquids and Dry syrups sections in it and has large no. of new molecules in our kitty.
The oncology, beta lactum & Cephalosporin blocks are completely separated i.e. All blocks are strucutly isolated and use completely separate air handling systems.
Oncology plant has latest technology compatible with OEL-5 (Operator exposure level), which is USFDA, MHRA approvable plant.
Specialization of Macofar Machine- It is a high speed powder filling machine equipped with online statistical check-weigher system to ensure that very vial has accurate measurement of powder in it. The machine is fitted with RABS to minimize the exposure of Drug to the operator and the environment, as per the latest guidelines of USFDA.
The OSD section of Cephalosporin’s is equipped with CFM vacuum transfer to provide powder transfer in a closed loop system.
The plant is designed at the RH of 15 which is suitable for Clavulanic acid preparation. All the core manufacturing areas are fitted with Dehumidifiers from Munters.
The water system is fitted with Zero dead lag valves of GEMU, Germany to ensure microbial free water. The water loop is fitted with Ozonators, to provide perfect sanitization.
Huge Capacity
The Cephalosporin section has got two filling lines of the speed 240 bottles per minute.
The Oncology plant is OEL-5 compatible (OEL-Operator exposure level). All the machines are CFR-21 part 11compliance with WIP (wash in place), CIP (clean in place) system inbuilt.
Oncology section is fitted with two lyophilizers, Lyofast-7 from IMA Edwards and has a capacity of approx. 20,000 vials per batch.
Oncology
We have setup an Oncology facility that is OEL-Level-5 compliant. We have isolators for sampling and dispensing and the manufacturing and mixing of the liquid parentals has SIP/CIP systems. The filling machines are fitted with close wrap technologies with 100% check weigh system and online partical monitoring. Both the temperature and humidity are maintained and controlled by BMS system. The AHUs are imported from Euroclima with Bibo facility. The line is integrated with 7.8 sq. mtr. IMA Edwards Lifolizer with semi-automatic filling of the lyo.
The OSD section has got single pot processor compression machine and coating with WIP facility compatible with OEL Level-5. All machineries are CFR-21 para-eleven compliant and plant has been designed as per US-FDA regulations.
Production Capacity
Tablet
manu capacity of 5Lacs per shift
Capsule
5 lacs per shift
Dry Syrup
capcity of 40,000 bottles with 30ml per shift
Sterile Dry Powder Injection
capacity of 2lacs vials per shift
Liq Inj
48000 vials per shift
Lyophilized inj
30000 vials per cycle
